Longevity

NAD+

Coenzyme

Also referred to as nicotinamide adenine dinucleotide.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells that functions as an electron carrier in metabolic redox reactions and as a substrate for enzymes that regulate metabolism, DNA repair, and aging-related signalling pathways. It also serves as a co-substrate for ADP-ribosylation. It is not a peptide.

Research has examined NAD+ in the context of cellular metabolism, mitochondrial function, and age-related decline, spanning both preclinical models and human studies.

Published on NAD+

Research OverviewNAD+ Combinations: What the Research Says About StackingNAD+ (nicotinamide adenine dinucleotide) is a redox cofactor and cosubstrate found in every living cell, functioning as a central mediator of cellular energy metabolism and a required substrate for several classes of regulatory enzymes.
Research OverviewNAD+: Research Outcomes and What Studies ReportNAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in all living cells that functions as an essential electron carrier in cellular redox reactions and as a cosubstrate for a range of non-redox signaling enzymes.
Research OverviewIs NAD+ Safe? Side Effects and Risks in the ResearchNAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells that functions as both an electron carrier in redox reactions and a substrate for enzymatic processes including ADP-ribosylation and adenylation.
Research OverviewWhat Is NAD+ Studied For?NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells that functions as an electron carrier in redox reactions and as a substrate for enzymes that regulate metabolism, DNA repair, and aging-related processes.