Metabolic

AOD-9604

Lipolytic hGH Fragment

Also referred to as AOD9604.

AOD-9604 is a synthetic peptide derived from the C-terminal region of human growth hormone, spanning amino acids 177–191, with a tyrosine residue added at the N-terminus. That structural modification distinguishes it from the unmodified hGH fragment 176–191, and early preclinical work focused on whether it could replicate hGH's fat-metabolism effects without the diabetogenic side effects of full-length growth hormone.

The published literature is sparse. Human clinical trial activity appears in registry entries from 2004–2005, but full trial results have not been published in the peer-reviewed literature. Three of the eight primary studies come from a single journal, and the absence of follow-on trial data is itself a noteworthy feature of this research base.

Published on AOD-9604