Metabolic

5-Amino-1MQ

NNMT Inhibitor

Also referred to as 5-amino-1-methylquinolinium.

5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in NAD+ metabolism and cellular energy regulation. The compound belongs to a class of methylquinolinium derivatives developed to selectively block NNMT activity.

The published evidence comes entirely from preclinical animal models and in vitro cell-line work. No human clinical trials have been reported. Research has examined the compound primarily in the context of metabolic disease, obesity, and cancer biology.

Published on 5-Amino-1MQ

Research Overview5-Amino-1MQ Peptide: What It Is and What Research Has Examined5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in NAD+ metabolism and cellular energy regulation.